Review
Prenatal cell-free DNA (cfDNA) screening, additionally called noninvasive prenatal screening, is an approach to display for sure chromosomal problems in an unborn child.
Throughout prenatal cell-free DNA screening, DNA from the mom and unborn child is removed from a maternal blood sample and evaluated for the boosted opportunity of certain chromosome troubles, such as Down syndrome, trisomy 13 as well as trisomy 18. This screening can also offer information regarding fetal sex.
Prenatal cell-free DNA testing is recommended for women that are at least 10 weeks expectant and also have ample counseling regarding the alternatives, advantages and also restrictions of first and also 2nd trimester screening and diagnostic testing. Your healthcare provider or a hereditary counselor will go over whether prenatal cell-free DNA testing may benefit you and also exactly how to interpret the results.
Why it's done
Prenatal cell-free DNA testing is offered to any individual who is expecting. It can be made use of to evaluate for certain chromosomal disorders, consisting of:
Down syndrome (trisomy 21).
Trisomy 18.
Trisomy 13.
It can also be used to evaluate for fetal sex.
Some prenatal cell-free DNA testing tests could also screen for the boosted opportunity of:.
Trisomy 16.
Trisomy 22.
Triploidy.
Sex chromosome aneuploidy.
Particular problems triggered by a chromosomal removal (microdeletion syndrome).
Specific single-gene problems.
Prenatal cell-free DNA testing could be more delicate and certain than standard first as well as second trimester testing, such as the initial trimester testing and also the quad screen. Furthermore, prenatal cell-free DNA screening might help females who have particular risk factors make decisions concerning invasive testing that brings a mild threat of losing the unborn baby, including amniocentesis as well as chorionic villus sampling (CVS). |
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